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Deslanosid

NMR下載 COA and HPLC MSDS下載
names：
Deslanosid
CAS號：
17598-65-1
MDL Number：
MF(分子式)： C47H74O19 MW(分子量)： 943.09
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	4-((3S,5R,8R,9S,10S,12R,13S,14S,17R)-12,14-dihydroxy-3-(((2R,4S,5S,6R)-4-hydroxy-5-(((2S,4S,5S,6R)-4-hydroxy-5-(((2S,4S,5S,6R)-4-hydroxy-6-methyl-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one
英文別名	Deslanosid; Ceglunat; Lekozid; Lanatosid C; Sediranido;
CAS號	17598-65-1
Inchi	InChI=1S/C47H74O19/c1-20-41(64-36-16-30(50)42(21(2)60-36)65-37-17-31(51)43(22(3)61-37)66-44-40(56)39(55)38(54)32(18-48)63-44)29(49)15-35(59-20)62-25-8-10-45(4)24(13-25)6-7-27-28(45)14-33(52)46(5)26(9-11-47(27,46)57)23-12-34(53)58-19-23/h12,20-22,24-33,35-44,48-52,54-57H,6-11,13-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27-,28+,29+,30+,31+,32-,33-,35+,36+,37+,38-,39+,40-,41-,42-,43-,44+,45+,46+,47+/m1/s1
InchiKey	OBATZBGFDSVCJD-LALPQLPRSA-N
分子式 Formula	C47H74O19
分子量 Molecular Weight	943.09
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產品說明	Deslanosid(CAS:17598-65-1):僅限應用于工業或者科學研究過程中非醫療目的，不應用于人類或動物的臨床診斷以及治過程療，該產品非藥用，非食用。
Introduction	Deslanosid is a cardiotonic glycoside from the leaves of Digitalis lanata.
Application1
Application2
Application3

警示圖
危險性	Warning
危險性警示
安全聲明
安全防護
備注

[1]Chen DP, Xiong YJ, Tang ZY, Yao QY, Ye DM, Liu SS, Lin Y. Characteristics of deslanoside-induced modulation on jejunal contractility. World J Gastroenterol. 2012 Nov 7;18(41):5889-96. doi: 10.3748/wjg.v18.i41.5889. PubMed PMID: 23139604; PubMed Central PMCID: PMC3491595.

[2]Gillis RA, Jolson H, Thibodeaux H, Levitt B. Antagonism of deslanoside-induced cardiotoxicity by combined nicotinic and muscarinic blockade of autonomic ganglia. J Pharmacol Exp Ther. 1975 Oct;195(1):126-32. PubMed PMID: 241837.

[3] Bakke OM, Aslaksen A, Lehmann V, Lien E. Pharmacokinetics and serum concentration--effect relationship of intravenous deslanoside. J Cardiovasc Pharmacol. 1981 Sep-Oct;3(5):1015-25. PubMed PMID: 6168847.

[4] Helke CJ, Kellar KJ, Gillis RA. Effect of in vivo deslanoside on the uptake of serotonin into platelets. Arch Int Pharmacodyn Ther. 1979 Nov;242(1):44-9. PubMed PMID: 543748.

[5] Klys M, Gross A. Determination of deslanoside in antemortem and postmortem specimens. Unusual case report. Forensic Sci Int. 1990 Apr;45(3):231-8. PubMed PMID: 2193860.

6: Tada A, Kitazawa M, Horasawa K, Zenda H, Kawa S, Oguchi T, Honma T, Furuta S. [Pharmacokinetics of deslanoside in man]. Yakugaku Zasshi. 1982 Nov;102(11):1061-6. Japanese. PubMed PMID: 7182446.7: Kobayashi M, Shimotori M, Chiba S. Direct effects of digoxin and deslanoside on sinoatrial conduction in isolated, blood-perfused dog atria. Jpn Heart J. 1983 Jul;24(4):649-55. PubMed PMID: 6645055.8: Ambrosioni E, Costa FV, Bracchetti D. Comparison of hemodynamic effects induced by pentaformilgitoxin and deslanoside in patients with heart failure. Int J Clin Pharmacol Biopharm. 1979 Oct;17(10):416-20. PubMed PMID: 500257.9: Marzo A, Ghirardi P, Maggi GC, Tornaghi A, Di Roberto F, Arisi GP. Plasma turnover and biliary and urinary excretion of deslanoside C-3H in man. Farmaco Prat. 1980 May;35(5):265-9. PubMed PMID: 7449946.10: Helke CJ, Souza JD, Gillis RA. Interaction of serotonin and deslanoside on cardiac rhythm in the cat. Eur J Pharmacol. 1978 Sep 15;51(2):167-77. PubMed PMID: 699982.1

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