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Renin inhibitory peptide

NMR下載 COA and HPLC MSDS下載
names：
L-prolyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-L-phenylalanyl-L-phenylalanyl-L-valyl-L-tyrosyl-L-lysine
CAS號(hào)：
75645-19-1
MDL Number：
MF(分子式)： C69H87N15O12 MW(分子量)： 1318.54
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	L-prolyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-L-phenylalanyl-L-phenylalanyl-L-valyl-L-tyrosyl-L-lysine
英文別名	Renin inhibitory peptide; Pro-his-pro-phe-his-phe-phe-val-tyr-lys;
CAS號(hào)	75645-19-1
Inchi	InChI=1S/C69H87N15O12/c1-42(2)59(67(93)81-54(35-46-25-27-49(85)28-26-46)61(87)76-51(69(95)96)22-12-13-29-70)83-65(91)55(34-45-20-10-5-11-21-45)78-62(88)52(32-43-16-6-3-7-17-43)77-64(90)56(36-47-38-71-40-74-47)79-63(89)53(33-44-18-8-4-9-19-44)80-66(92)58-24-15-31-84(58)68(94)57(37-48-39-72-41-75-48)82-60(86)50-23-14-30-73-50/h3-11,16-21,25-28,38-42,50-59,73,85H,12-15,22-24,29-37,70H2,1-2H3,(H,71,74)(H,72,75)(H,76,87)(H,77,90)(H,78,88)(H,79,89)(H,80,92)(H,81,93)(H,82,86)(H,83,91)(H,95,96)/t50-,51-,52-,53-,54-,55-,56-,57-,58-,59-/m0/s1
InchiKey	AIRMFERKNRDUKD-PVGXKDMPSA-N
分子式 Formula	C69H87N15O12
分子量 Molecular Weight	1318.54
溶解度Solubility
性狀	Solid powder
儲(chǔ)藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說(shuō)明	Renin inhibitory peptide(CAS:75645-19-1):僅限應(yīng)用于工業(yè)或者科學(xué)研究過(guò)程中非醫(yī)療目的，不應(yīng)用于人類或動(dòng)物的臨床診斷以及治過(guò)程療，該產(chǎn)品非藥用，非食用。
Introduction	Renin inhibitory peptide is an angiotensinogen analog.
Application1
Application2
Application3

警示圖
危險(xiǎn)性	Warning
危險(xiǎn)性警示
安全聲明
安全防護(hù)
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[1]Fitzgerald C, Aluko RE, Hossain M, Rai DK, Hayes M. Potential of a renin inhibitory peptide from the red seaweed Palmaria palmata as a functional food ingredient following confirmation and characterization of a hypotensive effect in spontaneously hypertensive rats. J Agric Food Chem. 2014 Aug 20;62(33):8352-6. doi: 10.1021/jf500983n. Epub 2014 Aug 7. PubMed PMID: 25062358.

[2]Fitzgerald C, Mora-Soler L, Gallagher E, O'Connor P, Prieto J, Soler-Vila A, Hayes M. Isolation and characterization of bioactive pro-peptides with in vitro renin inhibitory activities from the macroalga Palmaria palmata. J Agric Food Chem. 2012 Aug 1;60(30):7421-7. doi: 10.1021/jf301361c. Epub 2012 Jul 19. PubMed PMID: 22747312.

[3] Thaisrivongs S, Pals DT, DuCharme DW, Turner SR, DeGraaf GL, Lawson JA, Couch SJ, Williams MV. Renin inhibitory peptides. Incorporation of polar, hydrophilic end groups into an active renin inhibitory peptide template and their evaluation in a human renin infused rat model and in conscious sodium-depleted monkeys. J Med Chem. 1991 Feb;34(2):633-42. PubMed PMID: 1995887.

[4] Lafarga T, Rai DK, O'Connor P, Hayes M. A Bovine Fibrinogen-Enriched Fraction as a Source of Peptides with in Vitro Renin and Angiotensin-I-Converting Enzyme Inhibitory Activities. J Agric Food Chem. 2015 Oct 7;63(39):8676-84. doi: 10.1021/acs.jafc.5b03167. Epub 2015 Sep 28. PubMed PMID: 26373334.

[5] Zusman RM, Burton J, Christensen D, Nussberger J, Dodds A, Haber E. Hemodynamic effects of a competitive renin inhibitory peptide in humans: evidence for multiple mechanisms of action. Trans Assoc Am Physicians. 1983;9

6:365-74. PubMed PMID: 6388104.

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